Search on: PMS 2 PROTEIN 
Descriptors Found: 1
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Descriptor English:   Mismatch Repair Endonuclease PMS2 
Descriptor Spanish:   Endonucleasa PMS2 de Reparación del Emparejamiento Incorrecto 
Descriptor Portuguese:   Endonuclease PMS2 de Reparo de Erro de Pareamento 
Synonyms English:   PMS 2 Protein
PMS-2 Protein
PMS1 Homolog 2, Mismatch Repair Protein
PMS2 Protein
Postmeiotic Segregation Increased S. cerevisiae 2
Postmeiotic Segregation Increased-S. cerevisiae-2  
Tree Number:   D08.811.074.766.250
D08.811.277.040.025.215.250
D08.811.277.352.335.350.600
D12.776.260.540.250
Definition English:   A MutL protein and component of the DNA MISMATCH REPAIR system. Its ENDONUCLEASE activity introduces SINGLE-STRAND DNA BREAKS which create entry points for EXO1 exonuclease to remove the strand containing the mismatch. It may also function in DNA DAMAGE signaling. 
History Note English:   2017 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   56466 
Unique Identifier:   D000070976 

Occurrence in VHL:
 

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